Ebola: Away from Panick to Planning

                                       

The raging outbreak of Ebola virus in West Africa, a strain never seen in the region, is scary indeed. To see and read about medical professionals who are supposed to know more than anyone in the society, fall helplessly in the line of duty is very frightening. And when the media love for anything drama is added; fear goes off the roof. Ebola is another of Africa’s brand-killers. And it seems to take the shine away from the story, of a continent that has been rising unprecedentedly in a post-financial crisis era, where economic growth is in short supply. Even the recent historic US-Africa Summit and its outcome were overshadowed by the world-wide panic over the viral contagion. Two African Heads of States of the affected countries even declined an opportunity to take pictures with the first  American President of African blood— preferring  to stay back to lead emergency efforts against the disease— a rarity in Africa, albeit.

As if to further add fear. The World Health Organization, the world’s leading health agency, has declared Ebola outbreak and spread a global public health emergency— an extraordinary health event, the third in recent years after swine flu and polio. The organization has further labelled the epidemic as ‘’out of controlled’’ and most recently observed that the over 2000 confirmed cases and more than 1000 deaths in the three affected countries, have been ‘’vastly underestimated.’’ Medicins San Frontier, a reputable international NGO, has signaled no end to the tunnel yet. MSF projects another six more months to contain the virus. While Ebola has struck panic at the core of the political, health and social establishment, as a killer, it pales greatly in comparison with Africa’s health challenges. Without a forward looking approach to address the roots of the virus, all the firefighting to contain Ebola could end up harming Africa more than the disease itself. In fact, what justifies the unprecedented local, national and global (dis) attraction over Ebola.

Price of Herding
The virus seems to have unleashed the animal within us, in the face of danger: fear, confusion and breakdown. Like ‘’sheep’’, African governments individually strive to appear as doing something:  suspending air travels to key destinations, even against a WHO’s advice that air travel poses low risks of transmission. One country issues a suspension, others follow seemingly without questioning. Those seemingly rational decisions, made by governments, citizens and companies on an individual basis, when taken together, may end up doing more harm than good— if no disproportionate action had been taken in the first place.

The cost to Africa as whole is high, and disproportionate on the affected economies. While it is difficult to put an exact estimate, the extent of damages to countries would depend in part on the duration of spread of the disease. Early projection from the World Bank has already revised the growth forecast for Guinea by 1 percentage point ($62million), almost half of what the government spends on health care a year. The Liberian Finance Minister has also revised downward the IMF country growth forecast of 5.9%[1].

The panic and confusion could be more disruptive than the disease itself. While one cannot put money value to life, the true economic costs of pandemics are usually way off the mortality figures.  For example, the outbreak of a relatively rare disease like Severe Acute Respiratory Syndrome (SARS) with 8,273 cases as of 2003, caused just over 800 deaths[2]. But in terms of damage to the global economy, the figure was more than $50 billion in less than a year, more than the value of Kenyan economy, the 4th largest in Africa. While we can only know for sure, whether present policy responses were overblown two years at least after the end of the outbreak, as humans there is a natural tendency to overprice the risks of viral transmission, even for a rare pathogen with statistically low risks like Ebola (MacNeil A, 2012).

 While the future economics cost may be high, does the biology and epidemiology justify the ‘’excessive fear.’’ This is not to underestimate its deadliness.

More than what
In fact, Ebola as well as other filloviruses are a major public health threat to Africa and the world.  Ebola kills, and takes away life from patients up to 9 out of 10 times, and does this within a short period of time, ranging to 21 days. So far, for a modest estimate, more than 1000 people have died, since the virus surfaced in Guinea in December 2013, and subsequently spread to neighboring Liberia and Sierra Leone and now Nigeria[3].

But with only 2300 confirmed cases in the history of filovirus outbreaks until recently, the share of Ebola in Africa’s disease burden is barely noticeable. Taking the present outbreak into consideration, of the more than 2000 people infected, it has taken the disease almost 9 months to kill half of them. Assuming everything stays constant, and the disease continues with the same rate of progression, then rough estimates of number of deaths by the end of the year, may not exceed 2500. I would reemphasize everything remains equal.

Without a doubt, Ebola is truly horrible, but on mortality scale, there are many dozens of other diseases that kill far more people in Africa. Ebola does not future on the top 100 killers. By the end of the year, preventable cholera would have killed almost 100000 people, that is, 50 times more Africans than Ebola since it emerged in 1976. How about AIDS, TB, Malaria?  According to the global burden of disease estimates, in every four months, Sierra Leone sees around 650 deaths from meningitis, 670 from tuberculosis, 790 from HIV/AIDS, 845 from diarrheal diseases, and more than 3,000 from malaria.

Yet even when measured against this worst outbreak in affected countries, Ebola has been responsible for just 2 percent of all deaths in Sierra Leone. It killed no one in the country in the months and years before that, and assuming this outbreak is controlled soon, years will pass before it kills anyone again. Besides spread, the current outbreak is not exceptional in terms of mortality rates, too. While the numbers of people who eventually die from the infection compare to those that survive in the present outbreak averages 64%, it pales in comparison to the 90% deaths in the Congo 2002-2003 outbreak, the Zaire 1995 and 1996 fatality rates of 79% and 88% respectively. Fatality rates can go as low as 25%, like the outbreak in Uganda in 2007-2008.

Even when the way in which the disease propagates is taken into consideration, Ebola is a relatively controllable disease. The public health tools are well known an effective: like avoiding fluid and contacts with infected persons. The viral infection is not as infectious as flu, which spread through air.  
               
Broken system
I could hear a scream!!! Cholera, TB, HIV and Malaria have effective treatments and even the cures are available. True.  So what? How many people have access to them? Do we have a capable system to take the often free and subsidized drugs to where they are most needed?

Health care systems in Africa continue to suffer from chronic neglect. While public spending on health care has improved, thanks to donor funding, when compared to what is needed, African governments are shockingly underinvesting in healthcare delivery for their populations. Guinea allocates only 7% of the government spending to health, far below the 15% target agreed by African leaders in Abuja. And the quality of allocation of funding leaves much to desire: Urban areas are far more privileged over rural areas. In fact, in 2000 during the Ebola virus outbreak in Gulu, Uganda, 71.3% of the population lived more than 5 km from the nearest health facility. But the percentage was only 0.7% in the capital city, Kampala (MacNeil A, 2012).  While health budget have almost remained flat, spending on military has grown by 9% almost doubling the annual growth rate of Africa.  Corruption in the healthcare sector is also rife[4]. Basic health care infrastructures are lacking. Health workers lack motivation.

 Health care workers are among the most marginalized category of professionals in Africa. While political assassination is often one-off events in Africa, doctors and nurses are endangered on a daily basis due to their poor working conditions. The already limited health workers are therefore pushed out of the continent to Europe and America where their skills are valued more. Even when health workers raised their voices, politicians rarely care. Nigerian doctors are on strike for the last two months because of low salaries[5]. And the consequences are dire for the population. For example, Africa accounts for 24 percent of all diseases in the world but only has 3 percent of the world’s health workforce. Guinea, the epicenter of the outbreak has only 331 laboratory workers to cater for its 10 million people, approximately one staff for every 30000 people. Little wonder that, the outbreak is suspected to have occurred earlier than December and was only reported four months after, when it could have been easily contained[6].  In neighboring Liberia, before the outbreak there were only 150 doctors for its 3.5 million people. As a consequence, health services are therefore exclusionary lending themselves to corruption, as patients—in particular those who can afford— do anything to get care[7]. More than 50 percent of Sierra Leoneans doctors work abroad.

 And for those that elect to stay and serve their motherland, they have to accept what could best be described as difficult working conditions. Lack of basic equipment, protective gloves and even sterilize needles.  They may even end up unwillingly in harm’s way, paying the ultimate price with their lives, which is barely recognized as a footnote in the history of failed health policies. For example, WHO estimates that for every 100 patients admitted to a hospital in Africa, 10 of them will acquire additional illnesses from the care provided by the health establishment. Abandoned by governments, hospitals in Africa have become hubs for disease transmission. More than 81 health-care workers have died and 170 infected, according to WHO.

Early warning systems for detecting and reporting the emergence of pandemic are also broken, too. In a recent review by WHO, on the minimum core public health competencies to meet the International Health Regulations, a global system of rules for alerting and responding collectively to global health threats, Africa lags far behind all other regions. Only 45% of human resources for health targets were met as compare to a global average of 66%. Health targets at the port of entry were missed with only 23% of the agreed measures was in place compared to 54% globally (World Health Organization , 2012).

Africa has shortsightedly underinvested in providing health care in an accessible and effective manner to its citizens, in particular the poor. And for that, the world seems to be paying a heavy price.

Whose security
With no cure available, all what is left is containment of the virus. Already limited health resources in Africa, have been diverted to providing surveillance and response. While this is critical, it is not clear the extent to which health care systems will benefits in lasting ways that could start to address the chronic obstacles to providing care for all African.

But as it stands, the bottom millions of Africans who are driven into poverty every year because of health care expenditures, will further find it difficult to access the limited numbers of doctors, buy drugs or even go about their daily struggles to earn just more than a dollar a day. Many health professionals are too busy worrying about their own safety at the moment, than provide health care to the many other illnesses afflicting Africans. For instance, the Kikwit, DRC, Ebola outbreak in 1995 resulted in the infection of 80 health care workers and the closure of Kikwit General Hospital for non-Ebola related activities, severely limiting the availability of medical care to the population of Kikwit (200,000), as well as surrounding areas (al (Khan et al., 1999)   


Nevertheless, for one thing, Ebola has introduced in an increasingly unequal African society, a frightening reality: the random nature of death. The poor have almost same chance of dying of Ebola like the rich, everything being equal.  And for once, African elites don’t have the option to buy their way into safety and protection through flying abroad for treatment—while abandoning a crumbling health care system they have neglected for so long through chronic under investment. Added is the inconvenience of not being able to fly freely, abroad.

But for the millions of poor, the fear is not Ebola, but the weight of a crumbling and distant health system, which only is noticed when the mess of its mismanagement threatens the comfort of the elites. They have lost trust in their healthcare system and governments and therefore reluctant and suspicious to seek critical care against Ebola from their health care professionals. Even foreign healthcare workers have been chased away by communities.

The Ebola fear extends even beyond Africa, too. Globalization and interdependency have together turned Africa’s sneeze into a cold-causer for the West. Because of the security threat, strengthening the global surveillance system is becoming a top priority for donors. The possibility of terrorists playing with an Ebola-like bug, has invited national security institutions into the search for antidotes. While the US Military has no biological weapon program, it is investing heavily in research against new and emerging viruses, which could threaten the health of its troops. For example, the US Military together with a private company have developed an experimental antiviral therapy, ZMAPP, provided to the two American health workers infected in Liberia.

Information about the biology and epidemiology of Ebola is crucial to finding a cure. In fact, it is a global public good for humanity.  But the ability to conduct research on infected Ebola samples is limited to only high containment laboratories found in Europe and America. Extensive funding has been channeled to research in the last decade and progress has been made in understanding the biology and potential likelihood of finding a cure or vaccine against the deadly virus ( Dias et al, 2010). Yet what is the use of this information, if the vaccines or potential treatment options developed will remain unfordable to those who need them the most.

The tendency to put intellectual property rights over human rights is a dividing line between Northern and Southern countries. How to balance the global public good nature of information on the pandemic viruses originating from Africa with global access to vaccines and other health commodities generated from the viral samples collected remain unclear. While Africa may not have to go down the Indonesian way by using Ebola virus samples as a bargaining tool, the international health crisis provides an opportunity to shape the global health security for the benefit of African peoples[8].   

While all the global attention on Ebola has already started translating into much needed funding for health[9], it remains unclear whether this is going to plug critical gaps in the performance of health systems. In particular, building sustainable health systems that are people centered as opposed to diseases. The track record of disease based interventions in Africa has in many ways been counterproductive for long-term strengthening of health system. The disproportionate allocation of donor funds to HIV/AIDS has led to internal brain-drain in most African countries. The already limited health workers continue to exodus in droves away from public hospitals to work with international organizations and NGOs funded disease programs that offer better wages, than what the government could pay (Abdul, 2013).

Realm of Ideas
But beyond strengthening health system, Africa needs to assert its voice in the global health security space, where her presence has barely been noticed, besides begging for support. What does global health security means for Africa? How should international support for global health security works for Africa? Unfortunately, African governments seem too busy chasing funds while the West frames the problem of global health security, select the tools for tackling Ebola, and even decide what mechanisms and values should govern global health security. In fact, a rough google scholar search shows only two African journal articles on global health security. Majority of the articles are from the West and rest from Asia

To be fair, African countries together with BRICS at the World Health General Assembly, WHO’s intergovernmental forum, have resisted the use of the word global health security in WHO’s work.  But besides grandstanding, they have failed to engage in norms-setting discourses which are shaping the global health security agenda. Some western countries unable to push global health security within WHO, have opted for a bilateral approach. A Global Health Security Initiative was launched in 2001, by the US, EU, Canada and Japan as an informal international partnership of likeminded countries to strengthen health preparedness and response globally to threats including pandemics. The US has launched its own agenda for global health security, which includes among other goals strengthening global norms around rapid and transparent reporting and virus sample sharing.  The participation of African countries is key to the initiatives.

While Ebola remains virulent more than ever, Africa needs to go beyond short-term, ad-hoc emergency and panic ways of working, to a forward looking approach which addresses the roots of health insecurity. The global scare of Ebola could be an opportunity to assess the cost benefit of global health surveillance system, and distribution of its costs: who relatively bears the largest burden and how to compensate for it, before committing to any global health security initiative that may end of undermining already weakened health systems in the long-run. This would require ensuring an incentive mechanism for producing vaccines and anti-viral therapies against Ebola which could correct for the ability to pay by African countries, where Ebola remains endemic.

Given that the burden of disease of filoviruses like Ebola is very low, without public funding, there’s little incentive for pharmaceutical company to produce a vaccine, to immunize millions of Africans which could cost over a 1 billion dollar of investment and takes more than 15 years. Even when the vaccines are available for free, it is unlikely that all those most in need of it would get it, due to health system bottlenecks.
In fact, Ebola is a wakeup call to our leaders, shaming them to take concrete actions to fix our broken health system.

 To move forward, Africa would need to come up with a common position on global health security. What values should guide an African owned global health security agenda? What are the priorities and mechanisms for its effective implementation?    A High Level Continental Forum on Global Health Security could be a platform to start talking about those issues. The African Health Strategy up for revision next year could provide an opportunity to bring the health systems strengthening agenda with that of global health security, and doing so in a way that reflect Africa’s long-term needs and capacities.





[5] Recently the Nigerian President sacked the former central bank government for announcing the disappearance of $20billion in oil revenue over an 18 month period. This is nearly equivalent to the total amount of money spent on health care in Nigeria a year. more than two times what the government spends on health a year
[7] Every year WHO estimates that about, 150 million people are pushed into extreme poverty by health care bills majority of which are in Africa
[8] Unlike H5N1, Ebola virus is not very valuable, transmission risks is statistically very low, as such the virus would rarely spread widely to have a significant global impact like the highly pathogenic airborne H5N1 flu virus.
[9] The World Bank has announced a $200million emergency fund to country worst affected. This comes on top of $100million earmarked for Ebola by World Health Organization. WHO has further calls for an additional $75 million to plug the gap in funding. Bilateral partners like US and EU have also pledged additional support. 



Works Cited


Abdul H Mussa, J. P. ( 2013). Vertical funding, non-governmental organizations, and health system strengthening: perspectives of public sector health workers in Mozambique. Human Resources for Health, 11:26.
Khan et al. (1999). The reemergence of Ebola hemorrhagic fever, Democratic Republic of the Congo, 1995.Commission de Lutte contre les Epidemies a Kikwit. . J Infect Dis 179: Suppl 1S76–S86.
Dias et al(2010). Effects of the USA PATRIOT Act and the 2002 Bioterrorism Preparedness Act on select agent research in the United States. Proc Natl Acad Sci U S A 107: 9556–9561.
MacNeil A, R. P. (2012). Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases? PLoS Negl Trop Dis 6(6): e1546.
World Health Organization . (2012). International Health Regulations (2005) SUMMARY OF STATES PARTIES 2012 REPORT ON IHR CORE CAPACITY . Geneva: WHO.
  

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